MEPSEVII® (vestronidase alfa-vjbk):
The first and only enzyme replacement therapy (ERT) for MPS VII
MEPSEVII is used to treat children and adults with Mucopolysaccharidosis VII (MPS VII, Sly syndrome). The effect of MEPSEVII on the central nervous system (brain and spinal cord) symptoms of MPS VII has not been determined.
MEPSEVII® (vestronidase alfa-vjbk):
The first and only enzyme replacement therapy (ERT) for MPS VII
MEPSEVII is used to treat children and adults with Mucopolysaccharidosis VII (MPS VII, Sly syndrome). The effect of MEPSEVII on the central nervous system (brain and spinal cord) symptoms of MPS VII has not been determined.
MPS VII is one of the 7 main types of MPS
MPS VII starts with a deficient enzyme needed for maintaining cell health.
MPS VII is one of the 7 main types of MPS
MPS VII starts with a deficient enzyme needed for maintaining cell health.

Getting started on MEPSEVII
Ultragenyx Pharmaceutical Inc. is committed to patients with MPS VII and their caregivers. Through UltraCare®, Ultragenyx is here to help with everything you need to get started on treatment with MEPSEVII.
Getting started on MEPSEVII
Ultragenyx Pharmaceutical Inc. is committed to patients with MPS VII and their caregivers. Through UltraCare®, Ultragenyx is here to help with everything you need to get started on treatment with MEPSEVII.
- A severe allergic reaction called anaphylaxis has occurred with MEPSEVII treatment, as early as the first dose.
- Your healthcare provider will monitor you closely for symptoms of an allergic reaction while you are receiving MEPSEVII and for 60 minutes after your infusion.
- Your healthcare provider will immediately discontinue the MEPSEVII infusion if you experience anaphylaxis.
- Your healthcare provider should talk to you about the signs and symptoms of anaphylaxis and about getting immediate medical treatment if you have symptoms.
- The most common side effects of MEPSEVII are:
- Leakage of MEPSEVII into the surrounding tissue during infusion
- Diarrhea
- Rash
- Severe allergic reaction (anaphylaxis)
- Infusion site swelling
- Swelling around the infusion site
- Severe itching of the skin
- One patient experienced a seizure during a fever while taking MEPSEVII.
- are pregnant, think you may be pregnant, or plan to become pregnant. There is not enough experience to know if MEPSEVII may harm your unborn baby.
- are breastfeeding or plan to breastfeed. There is not enough experience to know if MEPSEVII passes into your breast milk. Talk with your healthcare provider about the best way to feed your baby while you receive MEPSEVII.
These are not all the possible side effects of MEPSEVII. Call your healthcare provider for medical advice about side effects.