MPS VII overview
What is MPS VII?
Mucopolysaccharidosis VII (MPS VII or Sly syndrome) is a lysosomal disorder characterized by the deficiency of the β-glucuronidase (GUS) enzyme.
This deficiency results in GAG accumulation in cells throughout the body, leading to multisystem tissue and organ damage.
GAGs are mucopolysaccharides that build up in the cells of organs and tissues in patients with MPS VII.
MPS VII can lead to multisystem tissue and organ damage